PDGFB Antibody

Cusabio

PDGFB Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA By similarity. Li Fang, Arterioscler. Thromb. Vasc. Biol., Apr 2004; 24: 787 - 792. EJ Battegay, J. Cell Biol., May 1994; 125: 917. RA Seifert, J. Biol. Chem., Feb 1993; 268: 4473 - 4480. Jason Liu, Am J Physiol Lung Cell Mol Physiol, May 1998; 274: 702.

Human, Mouse, Rat

-20°C or -80°C

12352203