PDGFRalpha (D842I) Assay Kit

BPS Bioscience

PDGFRalpha (D842I) Assay Kit

7

Research Use Only

Platelet-derived growth factor receptor A or PDGFRalpha has been implicated in regulation of cell growth and survival, apoptosis, and differentiation. It has been identified as a potential target in eosinophilic leukemia cancer, inflammatory breast cancer, and gastrointestinal stromal tumors. The D842 mutation is found in gastrointestinal stromal tumors and is associated with resistance to tyrosine kinase inhibitors. The PDGFRalpha (D842I) Assay Kit is designed to measure PDGFRalpha (D842I) activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

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