PDK4-IN-1 (hydrochloride) [2310262-11-2]

MedChem Express

PDK4-IN-1 hydrochloride [2310262-11-2]

5

2310262-11-2

Research Use Only

99.51%

C22H20ClN3O2

393.87

PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity.

[H]Cl.O=C1C2=C(C=CC=C2)C(C3=CC=CC(C4=CN(C5CCNCC5)N=C4)=C13)=O

2°C to 8°C,-20°C,-80°C

12352200