PDK4-IN-2 [1616752-12-5]

TargetMol Chemicals

PDK4-IN-2 [1616752-12-5]

16

Research Use Only

C13H10O5

246.22

PDK4-IN-2 (compound 8), a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor, exhibits an inhibition concentration (IC 50) of 46 microM. By regulating bioenergetics and activating the tricarboxylic acid cycle [1], it enhances the ejection fraction in failing hearts.

O=C1C=2C(=C(O)C=C(C(OC)=O)C2)C(=O)C=C1C

-20°C

51202000