PE Anti-Human/Mouse IL-5 Antibody
RD22191F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Mouse
TargetIL5
Overview
- SupplierReddot Biotech
- Product NamePE Anti-Human/Mouse IL-5 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDTRFK5
- ConjugateRPE
- Gene ID3567
- Target nameIL5
- Target descriptioninterleukin 5
- Target synonymsB-cell differentiation factor I; colony-stimulating factor, eosinophil; EDF; eosinophil differentiation factor; IL-5; interleukin-5; T-cell replacing factor; TRF
- HostRat
- IsotypeIgG1
- Scientific DescriptionIL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203