PE Anti-Mouse CD119 Antibody

Reddot Biotech

PE Anti-Mouse CD119 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

GR-20

RPE

Ifngr1

interferon gamma receptor 1

CD119; If; Ifgr; IFN-g; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; INF-g receptor; interferon gamma receptor 1; interferon gamma receptor alpha-chain; Nk; Nktar

Rat

IgG2a

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-Oe≥ROe+/- chain. It is a class II cytokine receptor family member that serves as a IFN-Oe≥-binding chain associated with the IFN-Oe≥ beta chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-Oe≥ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-Oe≥ initiates and regulates a variety of immune responses.

Mouse

2°C to 8°C

12352203