PE Anti-Mouse CD62L Antibody
RD20232F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetSell
Overview
- SupplierReddot Biotech
- Product NamePE Anti-Mouse CD62L Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMel14
- ConjugateRPE
- Gene ID20343
- Target nameSell
- Target descriptionselectin, lymphocyte
- Target synonymsAI528707; CD62; CD62 antigen-like family member L; CD62L; L; LAM-1; LECAM; LECAM1; LECAM-1; leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 1; Lnhr; L-sel; L-selectin; Ly-2; Ly-22; Lya; Lyam; Lyam1; Lyam-1; Ly-m2; Ly-m22; lymph node homing receptor; lymphocyte antigen 22; lymphocyte surface MEL-14 antigen
- HostRat
- IsotypeIgG2a
- Scientific DescriptionCD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and na?ve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte rolling on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish na?ve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203