PE/AF594 Anti-Human CD62L Antibody

Reddot Biotech

PE/AF594 Anti-Human CD62L Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

DREG56

Double Conjugated

SELL

selectin L

CD62 antigen-like family member L; CD62L; gp90-MEL; LAM1; LECAM1; LEU8; leukocyte surface antigen Leu-8; leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; L-selectin; LYAM1; lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; TQ1

Mouse

IgG1

CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of na?ve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyers patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Human

2°C to 8°C

12352203