PECAM-1 / CD31 Antibody (clone 158-2B3)

LifeSpan BioSciences

PECAM-1 / CD31 Antibody (clone 158-2B3)

23

Human PECAM-1 / CD31

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. Optimal dilution of the PECAM-1 antibody should be determined by the researcher.. Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml), WB CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. Optimal dilution of the PECAM-1 antibody should be determined by the researcher.

Flow Cytometry, ImmunoFluorescence, Western Blot

Research Use Only

Monoclonal

158-2B3

0.2 mg/ml

Unconjugated

PECAM1

platelet and endothelial cell adhesion molecule 1

CD31; CD31 antigen; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; PECAM-1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1

Mouse

IgG1

Human

2°C to 8°C

12352203