PE/Cyanine7 Anti-Human CD161 Antibody

Reddot Biotech

PE/Cyanine7 Anti-Human CD161 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

HP-3G10

Double Conjugated

KLRB1

killer cell lectin like receptor B1

CD161; CLEC5B; C-type lectin domain family 5 member B; hNKR-P1A; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B, member 1; natural killer cell surface protein P1A; NKR; NKR-P1; NKRP1A; NKR-P1A

Mouse

IgG1

CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

Human

2°C to 8°C

12352203