PE/Cyanine7 Anti-Human CD183/CXCR3 Antibody

Reddot Biotech

PE/Cyanine7 Anti-Human CD183/CXCR3 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

G025H7

Double Conjugated

CXCR3

C-X-C motif chemokine receptor 3

CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; CMKAR3; C-X-C chemokine receptor type 3; G protein-coupled receptor 9; GPR9; interferon-inducible protein 10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Mouse

IgG1

Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohns disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.

Human

2°C to 8°C

12352203