PE/Cyanine7 Anti-Human CD58 Antibody

Reddot Biotech

PE/Cyanine7 Anti-Human CD58 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

TS2/9.1

Double Conjugated

CD58

CD58 molecule

ag3; CD58 antigen, (lymphocyte function-associated antigen 3); LFA3; LFA-3; lymphocyte function-associated antigen 3; surface glycoprotein LFA-3

Mouse

IgG1

CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of its cognate ligand, CD2, on the T cell surface.

Human

2°C to 8°C

12352203