PE/Cyanine7 Anti-Mouse CD183/CXCR3 Antibody

Reddot Biotech

PE/Cyanine7 Anti-Mouse CD183/CXCR3 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

CXCR3-173

Double Conjugated

Cxcr3

chemokine (C-X-C motif) receptor 3

Cd183; Cmka; Cmkar3; C-X-C chemokine receptor type 3; Cxcr; interferon-inducible protein 10 receptor; IP-10 receptor

Hamster

IgG

CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Mouse

2°C to 8°C

12352203