PE/Cyanine7 Anti-Mouse CD80 Antibody
RD30107F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetCd80
Overview
- SupplierReddot Biotech
- Product NamePE/Cyanine7 Anti-Mouse CD80 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID16-10A1
- Concentration0.2 mg/ml
- ConjugateDouble Conjugated
- Gene ID12519
- Target nameCd80
- Target descriptionCD80 antigen
- Target synonymsactivation B7-1 antigen; B7 protein; B71; Cd28; Cd28l; Ly5; Ly-5; Ly53; Ly-53; MIC17; T-lymphocyte activation antigen CD80; TSA1
- HostHamster
- IsotypeIgG
- Scientific DescriptionCD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203