Peldesine (dihydrochloride)

MedChem Express

Peldesine (dihydrochloride)

10

Research Use Only

99.63

C12H13Cl2N5O

314.17

Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC 50 s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP , respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC 50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research [1] [2] [3] [4] .

Cl[H].O=C1C(NC=C2CC3=CC=CN=C3)=C2N=C(N)N1.Cl[H]

2°C to 8°C

12352200