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ProductsBack/Pellitorine [18836-52-7]
Chemical Structure
Chemical Structure
Chemical Structure

Pellitorine [18836-52-7]

Research Use Only
AG-CN2-0009
AdipoGen Life Sciences
CAS Number18836-52-7
DownloadMSDS
Product group Chemicals
Estimated Purity>97%
Molecular Weight223.4
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Pellitorine [18836-52-7]
  • Delivery Days Customer
    10
  • CAS Number
    18836-52-7
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Molecular Formula
    C14H25NO
  • Molecular Weight
    223.4
  • Scientific Description
    Chemical. CAS: 18836-52-7. Formula: C14H25NO. MW: 223.4. Synthetic. Originally isolated from roots of Anacyclus pryrethrum and fruits of Piper nigrum. Tingling-inducing agent. Excellent stable model compound for sensory studies. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Anti-thrombotic. Anti-septic. Antiprotozoal, antimalarial activity. - Tingling-inducing agent. Excellent stable model compound for sensory studies [3]. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity [1, 2, 4]. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research [5]. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor [6]. Potential anti-cancer lead compound [7]. Anti-thrombotic [8]. Anti-septic [9]. Antiprotozoal, antimalarial activity [10]. Antagonist of the TRPV1 [11].
  • SMILES
    [H]N(CC(C)C)C(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])CCCCC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species: I.K. Park, et al.; J. Agric. Food Chem. 50, 1866 (2002)
  • Chemical constituents and bioactivity of Piper sarmentosum: T. Rukachaisirikul, et al.; J. Ethnopharmacol. 93, 173 (2004)
  • Stereoselective Enzymatic Synthesis of cis-Pellitorine, a Taste Active Alkamide Naturally Occurring in Tarragon: P. J. Ley, et al.; Eur. J. Org. Chem. 2004, 5135
  • Chemical constituents of the roots of Piper sarmentosum: P. Tuntiwachwuttikul, et al.; Chem. Pharm. Bull. (Tokyo) 54, 149 (2006)
  • HPLC assisted chemobiological standardization of alpha-glucosidase-I enzyme inhibitory constituents from Piper longum Linn - An Indian medicinal plant: S.V. Pullela, et al.; J. Ethnopharmacol. 108, 445 (2006)
  • ACAT inhibition of alkamides identified in the fruits of Piper nigrum: M.C. Rho, et al.; Phytochemistry 68, 899 (2007)
  • Pellitorine, a potential anti-cancer lead compound against HL6 and MCT-7 cell lines and microbial transformation of piperine from Piper Nigrum: G.C. Ee, et al.; Molecules 15, 2398 (2010)
  • Antithrombotic activities of pellitorine in vitro and in vivo: S.K. Ku, et al.; Fitoterapia 91, 1 (2013)
  • Anti-septic effects of pellitorine in HMGB1-induced inflammatory responses in vitro and in vivo: S.K. Ku, et al.; Inflammation 37, 338 (2014)
  • Antiprotozoal activity of Achillea ptarmica (Asteraceae) and its main alkamide constituents: J.B. Althaus, et al.; Molecules 19, 6428 (2014)