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Penitrem A [12627-35-9]

Research Use Only
P1952
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 647,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Penitrem A [12627-35-9]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Acetone, Methanol, and DMSO.
  • Scientific Description
    Neuroactive mycotoxin produced by Penicillum and Aspergillus; GABA-A potentiator, BK K+ channel inhibitor.; Tremortin A
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Moldes-Anaya A, Rundberget T, Fæste CK, et al. Neurotoxicity of Penicillium crustosum secondary metabolites: tremorgenic activity of orally administered penitrem A and thomitrem A and E in mice. Toxicon. 2012 Dec 15;60(8):1428-35. PMID: 23085423. Asano S, Bratz IN, Berwick ZC, et al. Penitrem A as a tool for understanding the role of large conductance Ca(2+)/voltage-sensitive K(+) channels in vascular function. J Pharmacol Exp Ther. 2012 Aug;342(2):453-60. PMID: 22580348. Moldes-Anaya AS, Fonnum F, Eriksen GS, et al. In vitro neuropharmacological evaluation of penitrem-induced tremorgenic syndromes: importance of the GABAergic system. Neurochem Int. 2011 Dec;59(7):1074-81. PMID: 21924313. Deschaux O, Bizot JC. Effects of penitrem A on rat's performances in passive avoidance and Morris water maze tests. Mycopathologia. 1997;138(2):99-104. PMID: 9433810.