Pentamidine-d4 (dihydrochloride) [1276197-32-0]

MedChem Express

Pentamidine-d4 dihydrochloride [1276197-32-0]

5

1276197-32-0

Research Use Only

C19H22D4Cl2N4O2

417.37

Pentamidine-d4 (dihydrochloride) is the deuterium labeled Pentamidine dihydrochloride. Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 microM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities[1][2][3][4].

N=C(C1=CC=C(C=C1)OC([2H])([2H])CCCC([2H])([2H])OC2=CC=C(C=C2)C(N)=N)N.Cl.Cl

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12352200