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Pentamidine dihydrochloride

Pentamidine dihydrochloride

T23132
TargetMol Chemicals
CAS Number50357-45-4
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Product group Chemicals
Molecular Weight413.34
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Pentamidine dihydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    50357-45-4
  • Category Supplier
    Chemical
  • Chemical Name
    Pentamidine dihydrochloride
  • Molecular Formula
    C19H26Cl2N4O2
  • Molecular Weight
    413.34
  • Scientific Description
    Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi (Pneumocystis jirovecii). Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases and phosphatase of regenerating liver inhibitor. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 uM.
  • Shelf life instruction
    3 years
  • SMILES
    NC(c(cc1)ccc1OCCCCCOc(cc1)ccc1C(N)=N)=N.Cl.Cl
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Nguewa, P.A., et al., Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin. Chem Biodivers, 2005. 2(10): p. 1387-400.
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