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ProductsBack/Peptide Histidine Isoleucine, pig [80458-29-3]

Peptide Histidine Isoleucine, pig [80458-29-3]

Research Use Only
P2832
LKT Laboratories
Estimated Purity≥97%
Product group Chemicals
€ 702,00
1 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Peptide Histidine Isoleucine, pig [80458-29-3]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥97%
  • Format
    Soluble in water, acid.
  • Scientific Description
    Endogenous peptide, involved in prolactin signaling, circadian rhythms, feeding behavior; VPAC2 agonist.; PHI
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Goursaud S, Focant MC, Berger JV, et al. The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a. FASEB J. 2011 Oct;25(10):3674-86. PMID: 21730107. Colwell CS, Michel S, Itri J, et al. Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R939-49. PMID: 12855416. Olszewski PK, Wirth MM, Shaw TJ, et al. Peptides that regulate food intake: effect of peptide histidine isoleucine on consummatory behavior in rats. Am J Physiol Regul Integr Comp Physiol. 2003 Jun;284(6):R1445-53. PMID: 12595279. Lelièvre V, Pineau N, Du J, et al. Differential effects of peptide histidine isoleucine (PHI) and related peptides on stimulation and suppression of neuroblastoma cell proliferation. A novel VIP-independent action of PHI via MAP kinase. J Biol Chem. 1998 Jul 31;273(31):19685-90. PMID: 9677397.