Bio-Connect

PerCP/Cyanine5.5 Anti-Human CD11b Antibody

RD21784F
Reddot Biotech
TargetITGAM
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PerCP/Cyanine5.5 Anti-Human CD11b Antibody
  • Delivery Days Customer
    5
  • Clone ID
    ICRF44
  • Gene ID3684
  • Target name
    ITGAM
  • Target description
    integrin subunit alpha M
  • Target synonyms
    antigen CD11b (p170); CD11 antigen-like family member B; CD11B; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; CR-3 alpha chain; CR3A; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; macrophage-1 antigen alpha subunit; MO1A; neutrophil adherence receptor alpha-M subunit; SLEB6
  • Scientific Description
    CD11b is a 165-170 kD type I transmembrane glycoprotein also known as Oe+/-Mintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin beta2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203