PerCP/Cyanine5.5 Anti-Human CD11b Antibody

Reddot Biotech

PerCP/Cyanine5.5 Anti-Human CD11b Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

ICRF44

Double Conjugated

ITGAM

integrin subunit alpha M

antigen CD11b (p170); CD11 antigen-like family member B; CD11B; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; CR-3 alpha chain; CR3A; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; macrophage-1 antigen alpha subunit; MO1A; neutrophil adherence receptor alpha-M subunit; SLEB6

Mouse

IgG1

CD11b is a 165-170 kD type I transmembrane glycoprotein also known as Oe+/-Mintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin beta2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

Human

2°C to 8°C

12352203