PerCP/Cyanine5.5 Anti-Rat CD44H Antibody

Reddot Biotech

PerCP/Cyanine5.5 Anti-Rat CD44H Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

OX-49

Double Conjugated

Cd44

CD44 antigen

AU023126; AW121933; AW146109; CD44 antigen; ECMR-III; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HERM; HERMES; hermes antigen; HUTCH-I; hyaluronate receptor; Ly-2; Ly-24; lymphocyte antigen 24; Pgp; Pgp-1; PGP-I; phagocytic glycoprotein 1; phagocytic glycoprotein I

Mouse

IgG2a

CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Rat

2°C to 8°C

12352203