Perforin Polyclonal Antibody

Reddot Biotech

Perforin Polyclonal Antibody

5

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

PRF1

perforin 1

cytolysin; HPLH2; lymphocyte pore-forming protein; P1; perforin 1 (pore forming protein); perforin-1; PFP

Rabbit

IgG

The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

Human, Mouse, Rat

-20°C

12352203