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Perillyl Alcohol [18457-55-1]

Research Use Only
P1770
LKT Laboratories
Estimated Purity≥85%
Product group Chemicals
€ 465,00
50 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Perillyl Alcohol [18457-55-1]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥85%
  • Format
    Soluble in ethanol and acetone. Insoluble in water.
  • Scientific Description
    Terpene found in various plant and fruit sources; farnesyl transferase, geranylgeranyl transferase, telomerase, Na+/K+ ATPase inhibitor.; L(-)-Perillyl alcohol, Isocarveol, Perilla alcohol
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Tabassum R, Vaibhav K, Shrivastava P, et al. Perillyl alcohol improves functional and histological outcomes against ischemia-reperfusion injury by attenuation of oxidative stress and repression of COX-2, NOS-2 and NF-kappaB in middle cerebral artery occlusion rats. Eur J Pharmacol. 2014 Sep 18. [Epub ahead of print]. PMID: 25240714. Imamura M, Sasaki O, Okunishi K, et al. Perillyl alcohol suppresses antigen-induced immune responses in the lung. Biochem Biophys Res Commun. 2014 Jan 3;443(1):266-71. PMID: 24309112. DA Fonseca CO, Teixeira RM, Silva JC, et al. Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation. Anticancer Res. 2013 Dec;33(12):5625-31. PMID: 24324108. Koyama M, Sowa Y, Hitomi T, et al. Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction. Oncol Rep. 2013 Feb;29(2):779-84. PMID: 23233050. Sundin T, Peffley DM, Gauthier D, et al. The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. Biochimie. 2012 Dec;94(12):2639-48. PMID: 22902867. Garcia DG, Amorim LM, de Castro Faria MV, et al. The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor. Mol Cell Biochem. 2010 Dec;345(1-2):29-34. PMID: 20689980. Stratton SP, Alberts DS, Einspahr JG, et al. A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. Cancer Prev Res (Phila). 2010 Feb;3(2):160-9. PMID: 20103724.