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WB analysis of A431 cell lysate using GTX85520 PERP antibody in (A) the absence and (B) the presence of blocking peptide. Dilution : 1 microg/ml
WB analysis of A431 cell lysate using GTX85520 PERP antibody in (A) the absence and (B) the presence of blocking peptide. Dilution : 1 microg/ml
WB analysis of A431 cell lysate using GTX85520 PERP antibody in (A) the absence and (B) the presence of blocking peptide. Dilution : 1 microg/ml

PERP antibody

GTX85520
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetPerp
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Overview

  • Supplier
    GeneTex
  • Product Name
    PERP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1 microg/mL. ICC/IF: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64058
  • Target name
    Perp
  • Target description
    PERP, TP53 apoptosis effector
  • Target synonyms
    1110017A08Rik; KCP; KCP1; KCP-1; keratinocyte-associated protein 1; KRTC; KRTCAP1; p53 apoptosis effector related to Pmp22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; PIG; PIGPC1; THW
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9JK95
  • Protein Name
    p53 apoptosis effector related to PMP-22
  • Scientific Description
    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2 , p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), PID/MTA2 (6), MTBP (7) and PERP (8), were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein (8-10). p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis (8). The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family (8).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203