PEX12 Polyclonal Antibody

Reddot Biotech

PEX12 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

PEX12

peroxisomal biogenesis factor 12

PAF-3; PBD3A; peroxin 12; peroxisome assembly factor 3; peroxisome assembly protein 12

Rabbit

IgG

This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).

Human

-20°C

12352203