PEX5 Polyclonal Antibody

Reddot Biotech

PEX5 Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

PEX5

peroxisomal biogenesis factor 5

PBD2A; PBD2B; peroxin-5; peroxisomal biogenesis factor 5; peroxisomal C-terminal targeting signal import receptor; peroxisomal import receptor 5; peroxisomal targeting signal 1 (SKL type) receptor; peroxisomal targeting signal 1 receptor; peroxisomal targeting signal import receptor; peroxisomal targeting signal receptor 1; peroxisome receptor 1; PTS1 receptor; PTS1-BP; PTS1R; PXR1; RCDP5

Rabbit

IgG

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Human, Mouse, Rat

-20°C

12352203