PF 03716556

MedChem Express

PF 03716556 [928774-43-0]

5

928774-43-0

Research Use Only

99.10

C22H26N4O3

394.47

PF 03716556 is a potent, selective, competitive and reversible acid pump (H+,K+-ATPase) antagonist with pIC50s of 6.026, 6.038 and 6.009 for porcine, canine, and human recombinant gastric H+,K+-ATPase, respectively. PF 03716556 is inactive against other receptors, ion channels, and enzymes. PF 03716556 has the potential for gastroesophageal reflux disease research[1].

CC1=CN2C=C(C=C(C2=N1)N[C@H]3C4=C(C=CC=C4OCC3)C)C(N(CCO)C)=O

-20°C,2°C to 8°C

12352200