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ProductsBack/PF-04217903 [956905-27-4]

PF-04217903 [956905-27-4]

Research Use Only
P2012
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 156,00
1 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    PF-04217903 [956905-27-4]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    DMSO 5 mg/mL (13.42 mM); Water Insoluble; Ethanol Insoluble
  • Scientific Description
    Triazolopyrazine; c-MET inhibitor.; PF04217903
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Sennino B, Ishiguro-Oonuma T, Schriver BJ, et al. Inhibition of c-Met reduces lymphatic metastasis in RIP-Tag2 transgenic mice. Cancer Res. 2013 Jun 15;73(12):3692-703. PMID: 23576559. Zou HY, Li Q, Lee JH, et al. Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitor. Mol Cancer Ther. 2012 Apr;11(4):1036-47. PMID: 22389468. Timofeevski SL, McTigue MA, Ryan K, et al. Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors. Biochemistry. 2009 Jun 16;48(23):5339-49. PMID: 19459657.