PF-06263276

MedChem Express

PF-06263276 [1421502-62-6]

10

1421502-62-6

Research Use Only

99.38

C31H31FN8O2

566.63

PF-06263276 (PF 6263276) is a potent and selective pan-JAK inhibitor, with IC 50 s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3 and TYK2, respectively [1] .

FC1=C(O)C=C(CC)C(C2=CC(NN=C3C4=NC5=C(CN(C(C6=NC=C(N7CCCCC7)N=C6)=O)CC5)N4)=C3C=C2)=C1

-20°C,2°C to 8°C

12352200