PF-06447475 [1527473-33-1]
P2100
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NamePF-06447475 [1527473-33-1]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatDMSO 61 mg/mL ; Water Insoluble; Ethanol Insoluble
- Scientific DescriptionLRRK2 inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Daher JP, Abdelmotilib HA, Hu X, et al. LRRK2 Pharmacological Inhibition Abates alfa-Synuclein Induced Neurodegeneration. J Biol Chem. 2015 Jun 15. [Epub ahead of print]. PMID: 26078453. Henderson JL, Kormos BL, Hayward MM, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32. PMID: 25353650.