PF-06456384 (trihydrochloride)

MedChem Express

PF-06456384 trihydrochloride

5

Research Use Only

99.77%

C35H35Cl3F3N7O3S2

829.18

PF-06447475 trihydrochloride is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 trihydrochloride can be used for parkinsons disease (PD) research.

N#CC1=CC(S(=O)(NC2=NC=NS2)=O)=CC=C1OC3=CC=C(C4=CC(C(F)(F)F)=CC=C4)C=C3C5=CC(CNCCC6CCNCC6)=NC=C5.[H]Cl.[H]Cl.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200