PF-06459988 [1428774-45-1]

TargetMol Chemicals

PF-06459988 [1428774-45-1]

9

1428774-45-1

Chemical

Research Use Only

PF-06459988

C19H22ClN7O3

431.88

PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor. PF-06459988 has high efficiency and high affinity for EGFRs double mutants containing T790M, and has minimal activity against WT EGFR. PF-06459988 makes a candidate drug for the treatment of cancer.

3 years

CO[C@H]1CN(C[C@@H]1COc1nc(Nc2cnn(C)c2)nc2[nH]cc(Cl)c12)C(=O)C=C

-20°C

12352200