PF-06726304
ORB422334
CAS Number1616287-82-1
Product group Chemicals
Molecular Weight446.33
Overview
- SupplierBiorbyt
- Product NamePF-06726304 [1616287-82-1]
- Delivery Days Customer16
- CAS Number1616287-82-1
- CertificationResearch Use Only
- Molecular FormulaC22H21Cl2N3O3
- Molecular Weight446.33
- Scientific DescriptionPF-06726304 is a selective EZH2 inhibitor with Ki values of 0.7 nM and 3 nM for WT EZH2 and Y641N respectively; also inhibits H3K27me3 with the IC50 value of 15 nM.
- SMILESCC1=CC(=C(C(=O)N1)CN2CCC3=C(C=C(C(=C3C2=O)Cl)C4=C(ON=C4C)C)Cl)C
- UNSPSC12352200