PF-06761281

MedChem Express

PF-06761281

10

Research Use Only

99.32

C13H17NO6

283.28

PF-06761281 (Compound 4a) is a potent, orally active, partial selective sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor with IC 50 values of 0.51, 13.2 and 14.1 microM against HEK NaCT , HEK NaDC1 and HEK NaDC3 , respectively [1] .

O=C(O)[C@](CCC1=CC(C)=CN=C1OC)(O)CC(O)=O

-20°C

12352200