PF-06952229

MedChem Express

PF-06952229 [1801333-55-0]

5

1801333-55-0

Research Use Only

99.92

C23H24ClFN4O3

458.91

PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction.?PF-06952229 is a promising antineoplastic?agent for the study solid tumors, especifically metastatic breast cancer [1] .

O=C(NC(CO)CO)C1=CN=CC=C1NC2=CC(C3=CC(Cl)=CC=C3F)=NC=C2C(C)C

-20°C,2°C to 8°C

12352200