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ProductsBack/PF-3450074

PF-3450074

Research Use Only

S0434

Product group Chemicals

Overview

Supplier
Selleck Chemicals
Product Name
PF-3450074
Delivery Days Customer
9
Certification
Research Use Only
Scientific Description
PF-3450074 (PF-74) is a specifical inhibitor of HIV-1 capsid protein (CA). PF-3450074 (PF-74) displays a broad-spectrum inhibition of HIV isolates with EC50 of 8-640 nM. PF-3450074 (PF-74) acts at an early stage of HIV-1 infection, inhibits viral replication by directly competing with the binding of nuclear host factors cleavage and polyadenylation specific factor 6 (CPSF6) and nucleoporin 153 (NUP153), and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle.
UNSPSC
12352200