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PF-3758309

HY-13007
MedChem Express
CAS Number898044-15-0
Product group Chemicals
Estimated Purity99.79
Molecular Weight490.62
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PF-3758309 [898044-15-0]
  • Delivery Days Customer
    10
  • CAS Number
    898044-15-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.79
  • Molecular Formula
    C25H30N8OS
  • Molecular Weight
    490.62
  • Scientific Description
    PF-3758309 (PF-03758309) is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation[1][2][3].
  • SMILES
    CC1=NC2=C(SC=C2)C(NC3=NNC4=C3CN(C(N[C@@H](C5=CC=CC=C5)CN(C)C)=O)C4(C)C)=N1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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