Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PFKFB1 Polyclonal Antibody at dilution 1:60
PFKFB1 Polyclonal Antibody
E-AB-13026
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePFKFB1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThis gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
- UNSPSC12352203