PFKFB1 Polyclonal Antibody

Reddot Biotech

PFKFB1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

6PF-2-K/Fru-2,6-P2ase 1; 6PF-2-K/Fru-2,6-P2ASE liver isozyme; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; F6PK; fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase; HL2K; PFK/FBPase 1; PFRX

Rabbit

IgG

This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

Human, Mouse, Rat

-20°C

12352203