Western Blot analysis of Human fetal brain tissue using PFN2 Polyclonal Antibody at dilution of 1:450
PFN2 Polyclonal Antibody
E-AB-12624
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePFN2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionThe protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
- UNSPSC12352203