PHD-1-IN-1

MedChem Express

PHD-1-IN-1 [2009343-14-8]

10

2009343-14-8

Research Use Only

99.54

C13H8N4

220.23

PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 microM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an Arg367-out pocket[1].

N#CC1=CC=C(C2=CC=CC3=NC=NN23)C=C1

-20°C,2°C to 8°C

12352200