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ICC/IF analysis of HeLa cells using GTX10880 PHD3 antibody. Green : primary antibody Red : Tubulin Blue : DAPI Dilution : 1:200 Fixation : 10% formalin Permibilization : 0.5% Triton-X100
ICC/IF analysis of HeLa cells using GTX10880 PHD3 antibody. Green : primary antibody Red : Tubulin Blue : DAPI Dilution : 1:200 Fixation : 10% formalin Permibilization : 0.5% Triton-X100
ICC/IF analysis of HeLa cells using GTX10880 PHD3 antibody. Green : primary antibody Red : Tubulin Blue : DAPI Dilution : 1:200 Fixation : 10% formalin Permibilization : 0.5% Triton-X100

PHD3 antibody

GTX10880
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Primate, Rat
TargetEGLN3
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Overview

  • Supplier
    GeneTex
  • Product Name
    PHD3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID112399
  • Target name
    EGLN3
  • Target description
    egl-9 family hypoxia inducible factor 3
  • Target synonyms
    HIFP4H3; HIFPH3; HIF-PH3; HIF-prolyl hydroxylase 3; HPH-1; HPH-3; hypoxia-inducible factor prolyl hydroxylase 3; PHD3; prolyl hydroxylase domain-containing protein 3; prolyl hydroxylase EGLN3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9H6Z9
  • Protein Name
    Egl nine homolog 3
  • Scientific Description
    Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at Pro-564, and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism.
  • Reactivity
    Human, Mouse, Primate, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203