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Phenethyl Isothiocyanate [2257-09-2]

Research Use Only
P2508
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 883,00
50 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Phenethyl Isothiocyanate [2257-09-2]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Insoluble in water. Soluble in ethanol, DMSO.; Density: 1.094g/ml
  • Scientific Description
    ITC found in cruciferous vegetables.; Phenylethyl mustard oil
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591. Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616. Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1alfa and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899. Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653. Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080. Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048. Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.