Phenethyl Isothiocyanate [2257-09-2]
P2508
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NamePhenethyl Isothiocyanate [2257-09-2]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatInsoluble in water. Soluble in ethanol, DMSO.; Density: 1.094g/ml
- Scientific DescriptionITC found in cruciferous vegetables.; Phenylethyl mustard oil
- Storage Instruction-20°C
- UNSPSC12352200
References
- Tusskorn O, Senggunprai L, Prawan A, et al Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells. BMC Cancer. 2013 Dec 5;13(1):571. PMID: 24304591. Stan SD, Singh SV, Whitcomb DC, et al. Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model. Nutr Cancer. 2013 Nov 6. [Epub ahead of print]. PMID: 24195616. Gupta B, Chiang L, Chae K, et al. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1alfa and VEGF expression in human glioma cells. Food Chem. 2013 Dec 1;141(3):1841-6. PMID: 23870899. Thomson SJ, Brown KK, Pullar JM, et al. Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2. Cancer Res. 2006 Jul 1;66(13):6772-7. PMID: 16818653. Yu R, Mandlekar S, Harvey KJ, et al. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 1998 Feb 1;58(3):402-8. PMID: 9458080. Yu R, Jiao JJ, Duh JL, et al. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res. 1996 Jul 1;56(13):2954-9. PMID: 8674048. Guo Z, Smith TJ, Wang E, et al. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice. Carcinogenesis. 1993 Jun;14(6):1167-73. PMID: 8508504.