Phenosafranin

Chemodex

Phenosafranin

10

81-93-6

Research Use Only

>80%

Chemical. CAS: 81-93-6. Formula: C18H15ClN4. MW: 322.79. Soluble in DMSO (20mg/ml). Phenosafranin is a phenazine dye which is an organic chloride salt having 3,7-diamino-5-phenylphenazin-5-ium as the counterion. It has a high binding affinity to triplex RNA compared to the parent duplex form, and binds through intercalation to both forms of RNA. This property makes it useful for staining plant cells and for the determination of hemoglobin, dopamine and serotonin. It binds also to double-stranded DNA. It has a role as a fluorochrome (e.g. to functionalize different reagents), a histological dye and a photosensitizing agent. Phenosafranin has also shown biological properties, such as inhibit nuclear localization of transglutaminase 2 without affecting its transamidase activity. Spectral Data: Absorbance lambdamax=519nm. - Phenosafranin is a phenazine dye which is an organic chloride salt having 3,7-diamino-5-phenylphenazin-5-ium as the counterion. It has a high binding affinity to triplex RNA compared to the parent duplex form, and binds through intercalation to both forms of RNA. This property makes it useful for staining plant cells and for the determination of hemoglobin, dopamine and serotonin. It binds also to double-stranded DNA. It has a role as a fluorochrome (e.g. to functionalize different reagents), a histological dye and a photosensitizing agent. Phenosafranin has also shown biological properties, such as inhibit nuclear localization of transglutaminase 2 without affecting its transamidase activity. Spectral Data: Absorbance lambdamax=519nm.

RT

12352200