Phorbol-12-myristate-13-acetate [16561-29-8]
P2857
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NamePhorbol-12-myristate-13-acetate [16561-29-8]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSoluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform. Insoluble in water or aqueous buffer.
- Scientific DescriptionPKC activator, carcinogen.; TPA, PMA, Tetradecanoylphorbol acetate, 4beta-Phorbol 12-myristate 13-acetate, Phorbol ester
- Storage Instruction-20°C
- UNSPSC12352200
References
- Poachanukoon O, Koontongkaew S, Monthanapisut P, et al. Macrolides attenuate phorbol ester-induced tumor necrosis factor-alfa and mucin production from human airway epithelial cells. Pharmacology. 2014;93(1-2):92-9. PMID: 24556631. Oskoueian E, Abdullah N, Ahmad S. Phorbol esters isolated from Jatropha meal induced apoptosis-mediated inhibition in proliferation of chang and Vero cell lines. Int J Mol Sci. 2012 Oct 24;13(11):13816-29. PMID: 23203036. Colombo D, Tringali C, Franchini L, et al. Glycoglycerolipid analogues inhibit PKC translocation to the plasma membrane and downstream signaling pathways in PMA-treated fibroblasts and human glioblastoma cells, U87MG. Eur J Med Chem. 2011 May;46(5):1827-34. PMID: 21388717. Birnboim HC. Factors which affect DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate. Can J Physiol Pharmacol. 1982 Nov;60(11):1359-66. PMID: 6295575.