Phospho-ATF4 (Ser219) Antibody

Cusabio

Phospho-ATF4 (Ser219) Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

ATF4

activating transcription factor 4

cAMP response element-binding protein 2; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB2; CREB-2; cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; TAXREB67; tax-responsive enhancer element B67; tax-responsive enhancer element-binding protein 67; TXREB

Rabbit

IgG

Cyclic AMP-dependent transcription factor ATF-4

ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA bindingprotein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. Sato T., Shimotohno K. J. Virol. 65:1420-1426(1991) Leiden J.M. Proc. Natl. Acad. Sci. U.S.A. 89:4820-4824(1992) Bridgeman A.M. Wright H. Nature 402:489-495(1999)

Human, Mouse

-20°C or -80°C

12352203