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Western blot analysis of Bub3 (Phospho-Tyr207)Antibody (arrow indicated) in U87 (A) and U87 EGFRvIII (B) cells in Mitosis.
Western blot analysis of Bub3 (Phospho-Tyr207)Antibody (arrow indicated) in U87 (A) and U87 EGFRvIII (B) cells in Mitosis.
Western blot analysis of Bub3 (Phospho-Tyr207)Antibody (arrow indicated) in U87 (A) and U87 EGFRvIII (B) cells in Mitosis.

Phospho-BUB3 (Tyr207) Antibody

CSB-PA117544
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBUB3
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Overview

  • Supplier
    Cusabio
  • Product Name
    Phospho-BUB3 (Tyr207) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID9184
  • Target name
    BUB3
  • Target description
    BUB3 mitotic checkpoint protein
  • Target synonyms
    BUB3 budding uninhibited by benzimidazoles 3 homolog; BUB3L; budding uninhibited by benomyl; budding uninhibited by benzimidazoles 3 homolog; hBUB3; mitotic checkpoint component; mitotic checkpoint protein BUB3; testicular tissue protein Li 27
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43684
  • Protein Name
    Mitotic checkpoint protein BUB3
  • Scientific Description
    Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.??Seeley T.W., Wang L., Zhen J.Y.Biochem. Biophys. Res. Commun. 257:589-595(1999)Tang Z., Shu H., Oncel D., Chen S., Yu H.Mol. Cell 16:387-397(2004)Logarinho E., Resende T., Torres C., Bousbaa H.Mol. Biol. Cell 19:1798-1813(2008)?
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203