Western blot analysis of extracts from JK cells (Lane 2), using Cyclin H (Phospho-Thr315) Antibody. The lane on the left is treated with antigen-specific peptide.
Western blot analysis of extracts from JK cells (Lane 2), using Cyclin H (Phospho-Thr315) Antibody. The lane on the left is treated with antigen-specific peptide.
Phospho-CCNH (Thr315) Antibody
CSB-PA916851
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetCCNH
Overview
- SupplierCusabio
- Product NamePhospho-CCNH (Thr315) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID902
- Target nameCCNH
- Target descriptioncyclin H
- Target synonymsCAK; CAK complex subunit; CDK-activating kinase complex subunit; CycH; cyclin-dependent kinase-activating kinase complex subunit; cyclin-H; MO15-associated protein; p34; p37
- HostRabbit
- IsotypeIgG
- Protein IDP51946
- Protein NameCyclin-H
- Scientific DescriptionRegulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. Maekelae T.P., Nature 371:254-257(1994). Fisher R.P., Cell 78:713-724(1994). The MGC Project Team; Genome Res. 14:2121-2127(2004).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203