Western blot analysis of extracts from COS7 cells (Lane 2), using BL-CAM (Phospho-Tyr807) Antibody.The lane on the left is treated with antigen-specific peptide.
Western blot analysis of extracts from COS7 cells (Lane 2), using BL-CAM (Phospho-Tyr807) Antibody.The lane on the left is treated with antigen-specific peptide.
Phospho-CD22 (Tyr807) Antibody
CSB-PA912726
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCD22
Overview
- SupplierCusabio
- Product NamePhospho-CD22 (Tyr807) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID933
- Target nameCD22
- Target descriptionCD22 molecule
- Target synonymsB-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
- HostRabbit
- IsotypeIgG
- Protein IDP20273
- Protein NameB-cell receptor CD22
- Scientific DescriptionMediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Wilson G.L., J. Exp. Med. 173-137-146(1991). Wilson G.L., J. Immunol. 150:5013-5024(1993). Stamenkovic I., Nature 345-74-77(1990).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203